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Jaguars vs Colts Predictions - Early Picks & Odds for Week 17

The Indianapolis Colts need a win and help to make the playoffs, and that means they must defeat the Jacksonville Jaguars at Lucas Oil Stadium in Week 17.

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Jaguars vs. Colts Prediction, Odds, Spread, Injuries, Trends for NFL Week 17

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49ers at Colts: Predictions, picks and odds for Monday Night Football

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Broncos Slide In Power Rankings After Getting Pounced On In Week 16 Loss

After 11 consecutive wins, the Denver Broncos have finally found their first loss since Week 3.

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Jaguars beat the Broncos: Here are the food deals, freebies fans can get for the win

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Jaguars’ Trevor Lawrence is finally living up to pre-draft hype, and team is Super Bowl contender

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Jaguars Trevor Lawrence thrives in key area vs. Broncos in Week 16 win

According to Pro Football Focus, when blitzed, Lawrence completed 13-of-16 passes for 192 yards with two touchdowns.

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Jaguars eye playoffs as Trevor Lawrence continues brilliance vs. Broncos

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Jacksonville Jaguars get good grades after beating Denver Broncos

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· 1d · on MSN

Colts vs. 49ers prediction: Indianapolis and San Francisco do battle with playoff positioning on the line

The San Francisco 49ers are in the playoffs. Week 16 has been kind to them. There are a couple of outcomes from a seeding perspective, based on how Monday night against the Indianapolis Colts goes. Oddsmakers believe the 49ers are nearly a touchdown better than the Colts. We will see if it plays out that way.

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A Colts fan’s rooting guide for Week 17: What Indy needs to keep playoff hopes alive

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Colts playoff picture: Scenarios, chances for Indianapolis to make postseason

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Colts vs. 49ers prediction, odds, start time: 'Monday Night Football' picks, best bets from proven model

SportsLine's model simulated Indianapolis vs. San Francisco on 'MNF' 10,000 times and reveals its NFL picks today

49ers vs Colts Predictions, Picks & Best Bets for Tonight's Monday Night Football Game

Get the best 49ers vs. Colts predictions and odds ahead of Week 16 Monday Night Football on December 22, 2025. Take the Over.

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Colts vs. 49ers: Three Bold Predictions for ‘Monday Night Football’ in Week 16

The Colts played it safe through the air in Rivers’s return to action in Week 15. With his passes lacking a bit of zip, it’s hard to take shots downfield. He had just 120 yards last week while throwing for a touchdown and an interception, and I’m expecting him to improve upon that performance against the Niners.

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'Monday Night Football' prediction, odds, spread, time: 49ers vs. Colts picks from expert on 18-4 run

The Indianapolis Colts will look to snap a four-game losing streak when they battle the San Francisco 49ers on Monday Night Football. San Francisco is coming off a 37-24 win over the Tennessee Titans on Sunday,

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Colts’ Playoff Odds Revealed After Crushing Loss to 49ers

The Indianapolis Colts have had a rollercoaster season under coach Shane Steichen with an 8-7 record heading into the final two games of the NFL season. Monday night’s 48-27 home loss to the San Francisco 49ers showed how far Steichen’s battered and bruised team still has to go in order to reach the mountaintop of the league.