Some of the early insights that linked mutations in cytoskeletal proteins to disease came from experiments that recapitulated the disease phenotype in transgenic mice that expressed mutant genes ...

A major challenge to the concept of gene therapy for dominant disorders is the silencing or repairing of the mutant allele. Supplementation therapy is an alternative approach that aims to bypass the ...

Human hair-derived keratin biomaterials may help to regenerate skeletal muscle and show promise in new research that would be significant to increase in both the new muscle tissue formation and muscle ...

The intermediate filament protein keratin 8 (K8) is critical for the development of most mouse embryos beyond midgestation. We find that 68% of K8-/- embryos, in a sensitive genetic background, are ...

Keratin is the type of protein that makes up your hair, skin, and nails. Keratin can also be found in your internal organs and glands. Keratin is a protective protein, less prone to scratching or ...

Collagen supports hair structure and scalp health, while keratin repairs hair strands and enhances hair smoothness and shine. Biotin enhances keratin production for stronger, thicker hair. For ...