Here's how you can catch all the action in Riley Leonard's first career start for the Indianapolis Colts vs. the Houston Texans in Week 18.

Monday Night Football schedule, TV channel, time, streaming information for San Francisco 49ers vs Indianapolis Colts NFL Week 16 game Dec. 22, 2025.

The Texans are up 13-10 following a promising drive in the second quarter. An Xavier Hutchinson 33-yard gain put Houston in the red zone, but it took six more plays for C.J. Stroud to connect with Jayden Higgins for an 11-yard touchdown reception.

The San Francisco 49ers are taking on the Indianapolis Colts at 5:15 p.m. PDT on Dec. 22 at Lucas Oil Stadium on Monday Night Football.

C.J. Stroud accounted for two touchdowns and Ka’imi Fairbairn made a go-ahead field goal with 12 seconds left to lift the Houston Texans to a 38-30 win over the Indianapolis Colts on Sunday that extended their winning streak to nine games.

The Indianapolis Colts complete their season today with a visit to the Houston Texans in NFL Week 18 action: Score, live updates, start time, TV.

Colts Finally Get Their Day, Time Set for Week 18 Season Finale The day and time for the Indianapolis Colts' Week 18 season finale on the road against the Houston Texans has final